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In the News

Journal of the American College of Cardiology Study Highlights Significant Role for EBT in Evaluation of Patients With Symptoms of Heart Disease .

Absence of Coronary Artery Calcium On EBT Coronary Artery Scan Identifies Major Subgroup of Symptomatic Patients With Very Low Probability of Significant Coronary Artery Blockage SO. SAN FRANCISCO, Calif.--(BUSINESS WIRE)--March 5, 2001-- Imatron Inc. (Nasdaq:IMAT - news) today announced an important publication by the American College of Cardiology in its February 2001 Journal. The study featured the use of EBT in evaluating patients with symptoms of coronary heart disease. Prof. Ralph Haberl and colleagues from the University of Munich described their results in a paper entitled, ``Correlation of Coronary Calcification and Angiographically Documented Stenoses in Patients With Suspected Coronary Artery Disease: Results of 1,764 Patients.''

This is the largest peer-reviewed, published, single-center study to date in which subjects at high risk of having coronary artery obstructions underwent both invasive coronary angiography and the simple, non-invasive EBT coronary artery scan to detect coronary artery calcification. Women were well represented, with 539 subjects in the total of 1,764 patients, and the authors reported that the EBT coronary artery scan was demonstrated to be equally accurate in women as in men and for all age groups. Of particular importance were the younger subjects, less than 40 years of age; 55% of whom had zero calcification and also were determined to have zero risk of obstructive coronary disease. Also highlighted in this study was the finding that the EBT coronary artery scan demonstrated sensitivity up to 99% in males and 100% in females. These important results afford the possibility of using EBT ``as a filter in symptomatic patients to reduce the number of invasive procedures which do not lead to interventions.''

The authors reported that EBT coronary artery scanning ``was especially helpful in patients up to the age of 50 years.'' It is critical to note that this important result was corroborated in this large group of patients who were at sufficiently high risk to warrant expensive and invasive coronary angiography.

S. Lewis Meyer, CEO of Imatron, applauded the work done by these prominent researchers, commenting, ``The appropriate use of Imatron's proprietary EBT coronary artery scan in select groups of patients with atypical chest pain could save millions of dollars in unnecessary coronary angiography expense and medical risk annually. The German findings complement those from the ongoing Emergency Room study at the Mayo Clinic in which zero ''calcium scores`` virtually rule out the possibility of severe coronary artery disease. We believe that health insurers will inevitably recognize the importance and cost effectiveness of the EBT coronary artery scan in specific at-risk patient groups.''

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